Over-the-counter Antidepressant medicines can be purchased without a prescription and are most often used for the treatment that may not require the direct supervision of a physician. If, after the treatment with over-the-counter Antidepressant products you aren’t seeing improvement, don’t hesitate to contact your physician. It’s important to learn how over the counter Antidepressant products you choose to buy work and what generic ingredients should you look for.