Azithromycin 250 mg is effective against susceptible bacteria causing infections of the middle ear, tonsillitis, throat infections, laryngitis, bronchitis and sinuses. It is also effective against certain sexually transmitted infectious diseases, such as non-gonococcal urethritis and cervicitis.
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Azithromycin should be taken at least one hour before or two hours after meals since it may bind to food and not be absorbed from the intestine. For most infections, azithromycin is taken once daily for a relatively short course of treatment (usually five days). The first dose is often a "double dose," twice as much as the remainder of the doses given.
Unlike erythromycin and clarithromycin, azithromycin is generally considered free of interactions with most other medicines. It is recommended that azithromycin not be taken at the same time as aluminum- or magnesium- based antacids because antacids will bind the azithromycin and prevent it from being absorbed from the intestine. Azithromycin may be used in pregnancy if the physician feels that it is clearly necessary.
Azithromycin is generally well tolerated. Rarer side effects include abnormal liver tests, allergic reactions, and nervousness. That may go away during treatment, include mild diarrhea, nausea, vomiting, or abdominal pain. If they continue or are bothersome, check with your doctor. Check with your doctor as soon as possible if you experience hearing loss or ringing in the ears.