Gabapentin 300 mg is an anti-seizure medication. Gabapentin is normally prescribed for the neuropathy associated with diabetes and AIDS. It relieves neuropathy pain but also enhances mood, improves quality of life, and aids sleep. Gabapentin can also be used to treat partial seizures include treatment of severe, chronic pain caused by nerve damage, multiple sclerosis, or post-herpetic neuralgia. Studies are also looking at using gabapentin to treat manic-depressive disorder.
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Chronic pain may be treated with 300�3,600 mg per day, divided into three equal doses. When gabapentin is used for bipolar disorder, the starting dose is usually 300 mg taken at bedtime. Depending on the patient's response, the dose can be increased every four to seven days. Many people receive maximum therapeutic benefit at 600 mg per day, although some people have required up to 4,800 mg per day. The usual effective total daily dose is 900-3600 mg, administered in three divided doses per day; higher doses may be needed. Titration should proceed more slowly in elderly patients.
Sedation and confusion, as well as dizziness and ataxia, are the most common side effects, especially with rapid dose titration. Tolerance to these effects appears to develop within a few days if the dose is held at the highest tolerated dose until symptoms improve or stabilize. While these side effects usually go away on their own, if they last or are particularly troublesome, the patient should consult a doctor. More common side effects that occur when first starting to take gabapentin include blurred or double vision, muscle weakness or pain, swollen hand, feet, or legs, trembling or shaking, and increased fatigue or weakness.
Women who are breast-feeding and people who have decreased kidney functioning should discuss the risks and benefits of this drug with their physician. Women who are or wish to become pregnant will also require a careful assessment of the risks and benefits of gabapentin. Until an individual understands the effects that gabapentin may have, he or she should avoid driving, operating dangerous machinery, or participating in hazardous activities. Alcohol should be avoided while taking gabapentin.