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Over-the-counter Ketoconazole 200 mg can be purchased without a prescription and is most often used to treat symptoms of skin infections with fungi and yeasts that may not require the direct supervision of a physician. Ketoconazole is an antifungal OTC medication available as generic nizoral at online pharmacy OverTheCounterPharma.com.
Generic Nizoral tablet contains 2% Ketoconazole and is often prescribed for the treatment of fungal infections of the scalp and sebbhoreic dermatitis, however as it has anti androgenic properties it is used by some individuals in combination with other treatments in the treatment of androgenetic alopecia.
| Package | Price | Savings | Order | |
| Nizoral | £87.23 | £2.91 | Add to cart | |
| Nizoral | £166.57 | £2.78 | You save £7.89 | Add to cart |
| Nizoral | £237.98 | £2.64 | You save £23.72 | Add to cart |
| Nizoral | £301.45 | £2.51 | You save £47.48 | Add to cart |
| Nizoral | £428.40 | £2.38 | You save £95.01 | Add to cart |
Ketoconazole Indications
Ketoconazole, a synthetic imidazole dioxolane derivative, belongs to the antifungal class of drugs. Ketoconazole is indicated for the treatment of infections like fungal, ringworm and yeast and against Cushing�s disease (hyperadrenocorticism). The drug is efficient against serious fungal infections like coccidoidomycosis, blastomycosis and cryptococcosis, which affect lymph nodes, eyes, bone, skin and lungs.
How Ketoconazole works
Ketoconazole is fungicidal or fungistatic depending on concentrations. It inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochrome P450 enzyme 14 alpha demethylase and impair ergosterol synthesis. This will alter cell membrane and its permeability. This will results in loss of intracellular components. It also inhibits biosynthesis of triglycerides and phospholipids by fungi. It also inhibits several enzymes (e.g. Oxidative and peroxidative enzymes) which are involved in detoxification process. This will leads to cellular necrosis.
Ketoconazole Precautions
The drug is not recommended for use in pregnant or nursing animals. The medication should not be used within 2 hours of an antacid and with cisapride, astemizole or terfenadine. Extreme caution is required when used with phenobarbital, cyclosporine, theophylline, phenytoin, and anticoagulants such as warfarin. Make sure to inform the veterinarian or pharmacist about the medications the pet is taking. Administering the medication with food could reduce the side effects.
