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Over-the-counter Spironolactone usp 25 mg can be purchased without a prescription and is most often used to treat symptoms of the excretion of solutes and water that may not require the direct supervision of a doctor. Spironolactone usp is a Diuretic OTC medication available as generic aldactone at online pharmacy OverTheCounterPharma.com.

Spironolactone is a diuretic or "water pill" that is prescribed for people who have high blood pressure and for those who have swelling due to extra fluid. Spironolactone is often prescribed for young women with PCOS who are taking oral contraceptive pills. Spironolactone, the generic name for Aldactone, works by lowering androgen levels in the body. Androgens are hormones that both males and females have, but males have higher levels of them.

How should I use Spironolactone?

The recommended dose of spironolactone for adults ranges from 25 mg to 400 mg daily depending on the condition being treated. Spironolactone competitively inhibits adrenocortical hormone aldosterone activity in the distal renal tubules, myocardium, and vasculature. This agent may inhibit the pathophysiologic effects of aldosterone produced in excess by various types of malignant and benign tumors. Since this medication increases urine output, it is better to take it early in the day (with breakfast if you are taking a once-daily dose, or with breakfast and lunch if you are taking divided doses). Spironolactone may be taken with or without food. If stomach upset occurs, take the medication with food.

Cautions & warnings associated with Spironolactone

As diuretics cause your kidneys to produce more urine, you may prefer to take this medicine in the morning rather than before going to bed, as this will reduce the likelihood of you needing to get up in the night to visit the toilet. If you experience any of the following symptoms while taking this medicine you should inform your doctor promptly, so that the amount of fluids and salts in your body can be checked: thirst, lethargy, confusion, weakness, drowsiness, muscle cramps, scanty production of urine, abnormal heart rhythm, seizures, nausea or vomiting.